The Lakers take the short trip to Denver for the only time this season.
It is their first game since the disappointing defeat to the Orlando Magic on Sunday.
And James insisted that the approach for tonight will be the same as it always is.
The Lakers are going for their eighth win in 11 games tonight, as they look to recover from their shaky start to the season.
The Nuggets are on a good run of form, and defeated the Golden State Warriors earlier in the season when they had Steph Curry and Kevin Durant fully fit.
But James reassured fans that the team is not scared of Denver, and will look to put Sunday’s disappointment behind them.
“Last game is history,” he told reporters.
“We can’t keep going to the past.
“We want to get better.
“And tonight is a chance to do that.”
What time is the Los Angeles Lakers vs Denver Nuggets game on?
Tip-off tonight is 2am (Wednesday morning).
How can I watch the Los Angeles Lakers vs Denver Nuggets game?
Sky Sports are the exclusive rights holders for NBA in the UK.
However, tonight’s game will not be shown on Sky.
To stream the game for free, fans can watch through Bet365's website and apps, so long as they have funds in their account.
Alternatively fans can purchase the NBA League Pass.
There are numerous packages the NBA League Pass offers with the premium account offering coverage from every team, every game and exclusive features for an annual fee of £214.99.
The next one down covers every team and every game for an annual fee of £184.99 while if you wanted to stick to just one team then it will cost £99.99 for the season or a day pass will cost £4.99.